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In ariotlier embodiment, tlie SARM compound is of formula (n, (II), (III) or (IV)or its prodrug, analog, isonier, metabolite, derivative, pliarniaceutically acceptable salt, p11ar7iiaceutical product, polymorph, crystal, impurity, N-oxide, lrydrate or any combination tllereof, or a composition coniprising the sanae,. In another embodiment, the use of the SARM compounds is orally administer ed to said subject. In aiiotlier embodiment tlre SARM compound is of' fornzula (I), (II), (III) or (IV). CA 02543827 2006-04-26 WO 2005/120483 PCT/US2005/019788 derivative, pharnaaceuticall,y acceptable salt, pharniaceutical product, polymoiph, crystal, impurity, N-oxide, lrydrate or any combination tllereof, -or a composition comprising the sanle, unrivaled pharmaceuticals ostarine mk-2866. In anotlaer enlbodiment the SARM colTlpoLind is of formula (1), (IT), (III) or= (IV).. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome, unrivaled pharmaceuticals ostarine mk-2866.
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